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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMF1
All Species:
14.24
Human Site:
S436
Identified Species:
19.58
UniProt:
P82094
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P82094
NP_009045.2
1093
122842
S436
E
Q
C
E
P
A
E
S
Q
P
E
A
L
S
E
Chimpanzee
Pan troglodytes
XP_526227
1093
122795
S436
E
Q
C
E
P
A
E
S
Q
P
E
A
L
S
E
Rhesus Macaque
Macaca mulatta
XP_001088711
1092
122828
S435
E
Q
C
E
P
A
E
S
Q
P
E
A
L
S
E
Dog
Lupus familis
XP_533766
1089
122761
K434
Q
H
E
A
A
E
S
K
P
E
A
H
S
E
K
Cat
Felis silvestris
Mouse
Mus musculus
B9EKI3
1091
121796
N434
E
Q
C
E
A
V
E
N
Q
P
K
A
L
P
E
Rat
Rattus norvegicus
NP_446123
1093
121882
N435
E
D
G
E
A
A
E
N
H
P
K
A
P
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510334
1106
124384
E442
P
V
P
C
R
D
D
E
S
Q
P
E
V
L
F
Chicken
Gallus gallus
O42184
1433
161009
T534
K
H
I
D
D
V
D
T
S
L
S
L
L
Q
E
Frog
Xenopus laevis
Q5PQ23
649
75475
T103
L
R
M
S
D
L
S
T
D
E
E
E
M
K
R
Zebra Danio
Brachydanio rerio
NP_001003522
1136
126986
T462
Q
K
I
D
V
H
E
T
V
T
P
L
S
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572360
933
103794
R386
I
R
E
R
D
A
L
R
I
Q
M
K
S
L
R
Honey Bee
Apis mellifera
XP_394037
1326
150590
P475
I
K
N
K
V
E
M
P
S
G
I
S
S
N
D
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
V1067
L
D
K
Q
K
R
K
V
E
G
E
L
K
I
A
Sea Urchin
Strong. purpuratus
XP_785821
1176
131318
D441
D
V
E
S
E
D
Q
D
D
K
M
T
P
S
S
Poplar Tree
Populus trichocarpa
XP_002303293
975
109171
K429
R
K
V
Y
A
L
T
K
E
R
D
T
L
R
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WVL7
956
108335
L410
Y
H
Q
R
V
A
T
L
E
R
K
V
Y
A
L
Baker's Yeast
Sacchar. cerevisiae
P47166
707
81153
F161
E
T
T
D
S
S
F
F
K
L
I
K
E
K
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.5
93.1
N.A.
87.2
86.7
N.A.
81.2
21.7
22.6
59.7
N.A.
26.1
23.9
21
37.7
Protein Similarity:
100
99.4
99.1
96.1
N.A.
92.5
92
N.A.
88.3
39.9
37.3
74.6
N.A.
45.8
44.9
36.6
56.8
P-Site Identity:
100
100
100
0
N.A.
66.6
40
N.A.
0
13.3
6.6
13.3
N.A.
6.6
0
6.6
6.6
P-Site Similarity:
100
100
100
13.3
N.A.
80
53.3
N.A.
13.3
40
26.6
46.6
N.A.
13.3
33.3
26.6
20
Percent
Protein Identity:
25.8
N.A.
N.A.
27.1
21.1
N.A.
Protein Similarity:
47.2
N.A.
N.A.
45.4
39.4
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
6
24
36
0
0
0
0
6
30
0
6
6
% A
% Cys:
0
0
24
6
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
12
0
18
18
12
12
6
12
0
6
0
0
0
12
% D
% Glu:
36
0
18
30
6
12
36
6
18
12
30
12
6
6
36
% E
% Phe:
0
0
0
0
0
0
6
6
0
0
0
0
0
0
6
% F
% Gly:
0
0
6
0
0
0
0
0
0
12
0
0
0
0
0
% G
% His:
0
18
0
0
0
6
0
0
6
0
0
6
0
0
0
% H
% Ile:
12
0
12
0
0
0
0
0
6
0
12
0
0
6
0
% I
% Lys:
6
18
6
6
6
0
6
12
6
6
18
12
6
12
6
% K
% Leu:
12
0
0
0
0
12
6
6
0
12
0
18
36
12
12
% L
% Met:
0
0
6
0
0
0
6
0
0
0
12
0
6
0
0
% M
% Asn:
0
0
6
0
0
0
0
12
0
0
0
0
0
6
0
% N
% Pro:
6
0
6
0
18
0
0
6
6
30
12
0
12
6
0
% P
% Gln:
12
24
6
6
0
0
6
0
24
12
0
0
0
12
0
% Q
% Arg:
6
12
0
12
6
6
0
6
0
12
0
0
0
6
18
% R
% Ser:
0
0
0
12
6
6
12
18
18
0
6
6
24
24
6
% S
% Thr:
0
6
6
0
0
0
12
18
0
6
0
12
0
6
0
% T
% Val:
0
12
6
0
18
12
0
6
6
0
0
6
6
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
0
6
0
0
0
0
0
0
0
0
6
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _